SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e648cf675c3031388588cb90f09e98dda7bb8b431ba043999e7d5a44f0c60c8' 
  AND token = 'zHHatrcP3YGjBjK/ZsdnyTt5eJ4lXrQgo7nrfpoRffs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}