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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b20d498a7fa109c5ffc6ac509617b105841bdeebe8d6c1721681d736b491df3' 
  AND token = 'x8mgMHz4Fp2Fu0OIfyd38+oyCsYwBWZ9V779MC79eQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}