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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32d5f49f24058bd8818fdde2920336a71fb315279051367cdd9d9f20bc226675' 
  AND token = 'Gt6KkslZ+AZHYpREX+2o7/2eTEBn6tGWbSsDFT8g7i4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}