SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c7c595e7f91e78fe2ce401c1c58c77e962fa807ceb1950ca705576aee4c126' 
  AND token = 'UA0XbHiLuxA2WF59e9YJD4AerKdYtvLBEdZBAOrhgAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}