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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33bb5bdc0582a04f40da843173557dd4cf4a95be0149b54248a7f09800ce7469' 
  AND token = '1VAtPVl48biA2ir2+VQ9toyf8Pexzu7BANNDUk6oBaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}