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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d2e760eff659f1797936102a9a9e4db59ee4a0fea1e17cb26b7cedbfff8dd0' 
  AND token = 'xAmAw/2JES8QrAzbS0/0Vc5Oox20jRA5+dX1TjdCLX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}