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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d00dd5ed369d5cb994350348a54a2dc18f5b7a668d8b7537697b5903e7f06b1' 
  AND token = 'Sv+fE68f2i4rCVqnRDbt7mwOd59LDSNZS4v3w9vLerM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}