SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa0f5d125690423bf5dd13b7245ea6ed7dcd17639a713855a03a3773c2569455' 
  AND token = '0fAx66mATL8XKoef0mt74iqXAcNOQIgiTUKplCetv1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}