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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e15533a638721655138b1dfe0d6b43f0883ffa1c7a5175c285fe02fe17a9b2c2' 
  AND token = 'n+j3NbL74IfmOcl9jMImSM4SVQFmLuiWr7JEyPp3zng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}