SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e3a6ee0597811a90657f25524a5aa007780eeec1eec8ae6dfb8dfb407052308' 
  AND token = 'y2XtO6cBXY6tpXN0Er4fvMZSeb5L81Xj9G1CheTf2v8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}