SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d465b9a61af00c4e8ece5d7d15e1cd4f2f4ec4c0ccff1de51b28a54c9ccef7' 
  AND token = '2Ww+gA4gG/NLbtnFJt9nv9B4xirnJCuSjbKejxJo2cY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}