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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79b2d1f3ecf055fb57147470aac9d8223bcc3670d7444fcb80dd062192cd8285' 
  AND token = 'PITB7lM/3c4S1jjyY31M0zeqQuBe3ELSuQ4ERhQwKAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}