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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '472f781bd9465568aab6c45d3e7f3fd1c3096fd7c86fcb740fa3bfa953b6f0eb' 
  AND token = 'NeNLZXAYzKeO03+6A5CsaZeUvTq7d8ZJlSN4C/Sxuo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}