SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8376dc711a1a1810a1d863d6aecfa223784db97f4e9f70a6945459840ca0c6c' 
  AND token = '5AJHHViUNwzWsi4vvGOOVff2CEsw6RQxpzU73bSO+y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}