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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c216181af8dcb07778efd11f535d122b5cb5c61796a48d0ec1183b50e2f52767' 
  AND token = 'eE65cDWJ+UY2uEyg8BpitjQEYT3ePt3X5vUufOtTrFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}