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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab967d154e942eaeeaaa44294ed9d752bdf31b1f7a04d17d138f0df49d896a6' 
  AND token = 'YGnHItFIAm9bQ1SPT2wemNiGFiw6ZWdVLhtmoaWvS5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}