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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b95b23bd211b856d00eaa66d94cbbfa25819ba51735f3787c95700d7e5bd029' 
  AND token = 'PeiyTGXVpPiYwAUyKgrjS0W+OSNs1uCRyXZf4Sw6faw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}