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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68a4222b152c21f022836b9cf55f478de3fb91ed8cee7fa1ba31f51082c28fa3' 
  AND token = 'OzWnUOX+HOs7cr2VPMgxh4odTaPCWlS5AEqzx99hRQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}