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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b57e3e320e3f3e1d57da6504a21563f62bd70700197eff64da7c245a538881' 
  AND token = 'gKv29erO6Tww52xvRy0+t7Hc7VB/XtB7nNGLgb0nxa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}