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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d344d352b1b7e429c2b8035092b8ab066acd89fc1667773d9308b097d9d2afa' 
  AND token = 'dK/qOYeH5PIwvvT/puY8Iu2Sn426E0wPv4MAZ+7S/UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}