SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2db5ec554760cdc431c7150987d8787e76027cfb5969baf573207a3f3b2f3388' 
  AND token = '6erGMUIYfn6oGSrBFIFTjmWv96HXZrmHUQKvdPUYaLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}