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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '812c8a270024edc1c766cafcfeea243d15d6bb7a54eaf76a58788befea7df53f' 
  AND token = 'L+sUE1Fevkvq96tOS6BMmE+3q2oeQkbCfH0BATJ0DuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}