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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4949e01f74ad54bb8964575fe562dcb60d89923f0ad0012c8c1c42376ea748df' 
  AND token = 'KAuwzpv3mnQ8G4Y06oAehOMOo/i+IUW0oyQeFGWe2Vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}