SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bc5b9f655693e7c0ca6be097c42a7b4aaadf42a17b442e44a69130c394ba91d' 
  AND token = '3X0ZCQL9TBwBXIvyHyEFa7NVxLKcDiTQ42A+mFVuc6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}