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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '678796b0e5c845da60a187b86e1a5c88bb55cd63fc5b985fa15aa7c48dfa557f' 
  AND token = 'zOxZEHSBXlK5DUkHxFyF+lzRu2N8S59CGmkK5pTDmlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}