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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54a2024758c287a51f2397d0bb73db6648a566405d27fe16c96c649b241c0e05' 
  AND token = 'AI9atrQB0Qv1/9CcNoaJ02MAnrkY7hhCOfam1Q0X9iY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}