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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5496e45d777f291db20a47f97e1921d204e7e090969fbce6bba45c4c4e8e968d' 
  AND token = 'MQLXlA/GtdIFpx/xbKSKpn4mIPai166uouVvUdEd1Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}