SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aac654f49f90c00852d9da1a3dd29f476e66a9e6af929cb189f13e65fb9d1161' 
  AND token = 'P0txjivoh1hEtlUD8N1SX249raczkDWM2WrGpuW7dVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}