SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b7d99e72bae47be9c523422a2c07d151345eac48a2a709abfea7863475061b5' 
  AND token = 'uDk2p+6TMfk5sD++DFArtmnbb2FBd4Bp6tzBcdlJBAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}