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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e5dd73d43930d67237822b1b04390a8915f90f8331d4e90a7d628edbc2e1084' 
  AND token = 'F4Zkkz2nxcZjYdCPgwbuHzWeon5RK8+de00K/SM5/ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}