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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b23ce3ab99ea122e961911e89c6375c33a8c3e1ab5ad96e99e60ec0e215b1a88' 
  AND token = 'qS9MSOyCI26XrIOde+F47zSWIO3gWYkj9G75p/WKN48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}