SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a64ec900f1850c97cd7c2f6e43a52c90f35ab5c42f0e2d58e911c97b473a0373' 
  AND token = '5b12breyPKn1tUYyctyD6Dyh5bktnChIVueEA7geCe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}