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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c2551c5f55d3cb9e45eecf92bff6ea642be6b032dddc63c4f7bec23f9cf3d3f' 
  AND token = 'BJgG8c430c+S7RBW9Vz9B3n/gcdT2zuljxh1Fb7hkpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}