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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '059e2eefd6f1c5b3796bf8547f41fc826480bea3abc2ed9f90458f0229a78045' 
  AND token = 'rKhNIK/o6AZt5KTJzHArQ46sVG9fh4o9zLsbpQR44Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}