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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35e9fe3bdec50bedf94dd25628acbf63c5bfa49d4b4445d8f96c2e8d0c927fba' 
  AND token = 'oG7XbiBUx4+mgcvjHCfqudcR2Rkjuy8fEbpLzrIj5uI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}