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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aec3f22c977ee11518f31a1eadffe5224415d43971c85dfc83182bcb620d733f' 
  AND token = '10YgpQLacoKm7M3V1fFfq5b9BQGN6EwQ6LFfRkppCM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}