SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b1ca187471eb301946f0e4a3855c0236dfea1e78522df03469a0a91e0c0cd65' 
  AND token = 'oNFD7f6IynzYKDDjatE3FTuuDiakGPtdjmZezkyD8rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}