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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f5eca14f5c8a6ffff644a7055cd78e1eca6d214002d9d4944163b4f65da82af' 
  AND token = '/fluy67kC2MzmE+St+41vZJR3FYhp4DtLYXlMmesdsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}