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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e157f4d1b88088c3f4e9ed014cbe911c5cee0e8655c5c8c600d1c258baea38c' 
  AND token = 'xk1AAi1s54eAjhJIgJvKvjcQz/ZS2fRECWLWDom31JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}