SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4000da16dfce6f13bab6938df0874a09341434258be6c2133d1bff70a6b07275' 
  AND token = 'EqPmCoYI7G1IqJ21gYhwABELim+S1jAEUTNNn7sRw74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}