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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '342843b9b0e05f273a780bf384921b65221997e672eaf8c78e7e452cbb38858b' 
  AND token = 'lK1La1JYfuSNxUeOSxyd7niOwDJ7qfzhsg4dR2i7BhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}