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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd65bda0afe39bed687b33ed76250027f4fc5074dc2aac5662e3f26a07ed6656' 
  AND token = 'PlHmH7yGSTHFqPdyX1gMhYoj2ogL2L/r6YvmYcTwYeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}