SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc723c76a720225e9dab7700b7da20feefd39f727fe635b486deb1ebd3e286d9' 
  AND token = 'PmUlcIwwy3BVRyxpEUEgTZiuC3qLmY/7WoRnBrbVy/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}