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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241021b0b8dee64407b9ce98d52aa3aca4e52ec1720a2c81cb3792a517eb9514' 
  AND token = '5CHXrN1sihypaB6OP++W/klqjGyvDI7UIqCSRhM8kY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}