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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ad8a3057e1ab6e8045f1a73a40d48f161d85da5930500d72b76c93a6c5acb6c' 
  AND token = 'zgUOjy5vtOkoNQEwHsGgxCPO05eU5pS87enUfk+6avI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}