SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e549a00309d753a383b534a325ba26c8ec01118e375316dc0217551599195e65' 
  AND token = 'rTAbYIDpb/w3clbzPUXsWCMko1c41eHZWA+qe/2hohY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}