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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64b2955f333d92a56f80ce2bf56e1a145c39545f0d74ea8b4412bec108a2ff7a' 
  AND token = 'exZMh+4G5CpIAT6QF/MaDPEm36K0VgzFu3aTRX7CQ8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}