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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a7bf08e22b123ef94dae8af3f6c679df532c9eff99b31ca9a9e23fa6ed182a1' 
  AND token = 'PINRHB7wL2RxzW9pHFdXqNk2S5qvDl3PX9OYJOgkSxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}