SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '505355801d2b8e49390459ece4158d3d08c3f0a4c6b589d00bf91950af9532bc' 
  AND token = 'TigkLgBa5FCA7gQNjEMt3CHAxCua+5NlWR1VCxRC2Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}