SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86d6afa7295aaf9cc12f8f3fb6b847e9acf2ddc1dce40fa696213a71cb376994' 
  AND token = 'sGUSSdFeFvnOwtYHXH8mIIsQZXmiDQ571PsX2m1kg3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}